Comprehensive characterization of the postoperative pericardial inflammatory response: Potential implications for clinical outcomes

Ali Fatehi Hassanabad, Friederike I Schoettler,William D T Kent,Corey A Adams,Daniel D Holloway,Imtiaz S Ali,Richard J Novick,Muhammad R Ahsan,Robert Scott McClure,Ganesh Shanmugam,William T Kidd,Teresa M Kieser,Paul W M Fedak,Justin F Deniset

JTCVS Open（2022）

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摘要

These results show that cardiac surgery elicits profound alterations in the immune cell profile in the pericardial space. Defining the cellular and molecular mediators that drive pericardial-specific postoperative inflammatory processes may allow for targeted therapies to reduce immune-mediated complications.

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关键词

inflammation,pericardial space,postoperative pericardial fluid,conventional cardiac surgery,minimally invasive cardiac surgery

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