Predictive modelling for late rectal and urinary toxicities after prostate radiotherapy using planned and delivered dose.

The achieved NTCP parameters using modern RT techniques and accounting for organ motion differs from QUANTEC reported parameters. D-D of 77.9 Gy for GI and D/D-D of 81.7-81.9 Gy for GU demonstrated good predictability in determining the risk of Grade ≥2 toxicities especially for GI derived D and are recommended to incorporate as part of the DV planning constraints to guide dose escalation strategies while minimising the risk of toxicity.