Association Between Rheumatic Autoantibodies and Immune-Related Adverse Events.

Kristen Mathias,Sherin Rouhani,Daniel Olson,Anne R Bass,Thomas F Gajewski,Pankti Reid

The oncologist（2023）

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摘要

Pre-ICI RF was associated with higher odds of rheumatic-irAEs. IrAEs had better OS; therefore, clinical contextualization for rhAbs is critical to prevent unnecessary withholding of lifesaving ICI for fear of irAEs.

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关键词

arthritis,autoantibodies,cyclic citrullinated peptide,immune checkpoint inhibitors,immune-related adverse events,rheumatoid factor

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