Evaluating population structure of Ecuador for forensic STR markers

R. Flores-Espinoza, A.N. Angulo-Pozo, A. Garzón-Salazar,A. Cabrera-Andrade,E. Paz-Cruz,G. Burgos, L. Gusmão

Forensic Science International: Genetics Supplement Series(2022)

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摘要
The continuous admixture events among Europeans, Native Americans, and Africans occurred differently throughout the Ecuadorian territory, creating a diversified genetic composition. Therefore, to evaluate how the genetic diversity is partitioned along the country for 15 STRs, 842 admixed-population samples were analyzed. We also evaluated the effect of applying an adjustment for population structure when estimating LRs using a national database. The results showed that to accurately assess forensic evidence, the use of a national database may be justified with the application of an appropriate adjustment for population structure.
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关键词
Population structure,Theta-correction,STRs,Likelihood ratio,Forensic databases
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