YAP-Activated SATB2 Is a Coactivator of NRF2 That Amplifies Antioxidative Capacity and Promotes Tumor Progression in Renal Cell Carcinoma.

Juan Jin,Fen Chen,Wenfang He,Li Zhao,Bo Lin,Danna Zheng,Li Chen,Hongchao He,Qiang He

Cancer research（2023）

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摘要

A YAP-SATB2-NRF2 regulatory axis amplifies antioxidative stress signaling and provides potential therapeutic targets to enhance response to chemotherapy in renal cell carcinoma.

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关键词

renal cell carcinoma,amplifies antioxidative capacity,nrf2,promotes tumor progression,yap-activated

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