Optimization of determinant factors associated with the efficiency of experimental autoimmune uveitis induction in C57BL/6 mice.

Ming Yang, Zixuan Yang,Jiani Huang,Wangshu Yu,Xiaoying He,Minjie Yuan,Wei Han,Wei Chen

Annals of translational medicine（2022）

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摘要

This work optimized the protocols of EAU induction and obtained a high and stable induction rate with severe inflammation in the C57BL/6 mouse strain. Our results facilitate future experimental research involving uveitis.

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关键词

C57BL/6 mice,Experimental autoimmune uveitis (EAU),autoimmunity,induction protocol,pertussis

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