Factors associated with knowledge, attitudes and preventive practices towards COVID-19 in health care professionals in Lima, Peru [version 3; peer review: 2 approved]

Background: Nowadays, we are facing a disease caused by SARS-CoV- 2, known globally as COVID-19, which is considered a threat to global health due to its high contagiousness and rapid spread. Methods: Analytical cross-sectional study in 302 health professionals. An online questionnaire consisting of questions about knowledge, attitudes and practices (KAP) towards COVID-19 was applied. Socio- demographic, occupational and comorbidities factors were explored. Simple and multiple logistic regression models were used to identify factors associated with KAP. Results: Of the total, 25.2%, 31.5% and 37.4% had high levels of knowledge, preventive practices and risk perception attitudes respectively. Being married aOR=6.75 CI(1.46-31.2) p=0.014, having a master's degree aOR=0.4, CI(0.21-0.80) p=0.009, having a working day with less than ten hours ORa=0.49 CI(0.25-0.95) p=0.036 and obesity aOR=0.38 CI (0.15-0.95) p=0.039 were associated with a low level of knowledge of COVID-19. The variables associated with preventive practices were being over the age of 50 aOR=0.52 CI(0.27-0.98) p=0.007, working in the hospitalization area aOR=1.86 CI(1.08-3.18) p= 0.018 and having comorbidities such as arterial hypertension aOR=0.28 CI(0.081-0.99) p=0.02 and obesity aOR=0.35 CI(0.14-0.83) p=0.019. In relation to negative attitudes towards COVID-19, it was found that physical contact with patients with a confirmed diagnosis aOR=1.84 CI (1.14-2.97) p=0.006 and having asthma aOR=2.13 CI(1.081-4.22) p=0.029 were associated with these attitudes. Conclusion: Our study revealed that health professionals have an insufficient level of knowledge of COVID-19. This is why we recommend implementing strategies such as health literacy programs among health care workers. Thus, they can help develop positive