CeO2-Azacrown Conjugate as a Nanoplatform for Combined Radiopharmaceuticals
Nanomaterials(2022)
摘要
This study is one of the first attempts to assess CeO2 nanoparticles as a nanoplatform for radiopharmaceuticals with radionuclides. The process of functionalization using a bifunctional azacrown ligand is described, and the resulting conjugates are characterized by IR and Raman spectroscopy. Their complexes with 207Bi show a high stability in medically relevant media, thus encouraging the further study of these conjugates in vivo as potential combined radiopharmaceuticals.
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关键词
nanoceria,surface functionalization,radiolabeled nanoparticles,bismuth,radiopharmaceuticals
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