Successful Orthotopic Heart Transplantation With Positive Crossmatch in a Hyperimmunized Child on Mechanical Circulatory Support-Case Report

S. Pawlak,J. E. Sliwka,A. Wierzyk,H. Mado, K. Zwierzynska, J. Perlikowska, P. Zborowska, A. Sobieraj, P. Przybyowski

TRANSPLANTATION PROCEEDINGS(2022)

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摘要
In the pediatric population there is a shortage in the number of hearts available for transplantation. However, sometimes a heart transplant is urgently required to save lives. The problem arises when the patient is hyperimmunized and there is a positive crossmatch with the only available donor. We present such a case of a 9-year-old patient with dilated cardiomyopathy on ventricular assist device, in whom it was possible to perform a successful HT and also apply a successive prevention against graft rejection.
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关键词
Choline acetyltransferase,Cholinergic neuronal differentiation factor,Leukemia inhibitory factor,Spinal cord,Tissue culture
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