Lesion location across diagnostic regions in multiple sclerosis

Viola Pongratz,Matthias Bussas,Paul Schmidt,Sophia Grahl,Christiane Gasperi,Malek El Husseini,Laura Harabacz,Viktor Pineker,Dominik Sepp,Lioba Grundl,Benedikt Wiestler,Jan Kirschke,Claus Zimmer,Achim Berthele,Bernhard Hemmer,Mark Mühlau

NeuroImage: Clinical（2023）

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摘要

Across regions, new lesions do not occur randomly; instead, new lesions in the periventricular, juxtacortical and infratentorial diagnostic region are associated with that at baseline. Lesions in the subcortical regions are more closely related to periventricular lesions. Moreover, subcortical lesions substantially contribute to lesion burden in MS but are less likely to show gadolinium enhancement (than lesions in the diagnostic regions).

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关键词

Multiple sclerosis,Demyelinating diseases,Magnetic resonance imaging,White matter lesion

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