Tryptophan metabolites predict response after cognitive behavioral therapy for depression: A single-arm trial.

Maria S Simon,Elif Weidinger,Bianka Burger, Yasemin Kisla, Julia Niedeggen, Petra Thaler,Michael Zaudig,Ulrich Voderholzer,Markus Schwarz,Norbert Müller

Journal of Affective Disorders Reports（2023）

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摘要

•Tryptophan metabolites in relation to cognitive behavior therapy were firstly investigated.•5-HIAA, kynurenine, 3-HK, and kynurenine-tryptophan-ratio increased to endpoint.•all four parameters were indicative of treatment response.

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关键词

Depressive episode,Psychotherapy,Kynurenine,Serotonin,Inflammation,5-HIAA

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