Combined Cognitive Training and Vortioxetine Mitigates Age-Related Declines in Functional Brain Network Integrity.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry(2023)

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摘要
This preliminary study provides evidence that combining cognitive training with pro-cognitive medication may modulate the effects of aging on functional brain networks. Results indicate that for older adults experiencing age-related cognitive decline, vortioxetine has a potentially beneficial effect on the correspondence between aging and functional brain network segregation. These results await replication in a larger sample.
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关键词
Cognitive training,aging,cognitive decline,fMRI,resting state functional connectivity,vortioxetine
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