CARDIOTOXICITY AND PHARMACOGENETICS OF DOXORUBICIN IN BLACK ZIMBABWEAN BREAST CANCER PATIENTS.

Vincent Aketch Nyangwara,Tinashe Mazhindu,Zedias Chikwambi,Collen Masimirembwa,Thomas B Campbell,Margaret Borok,Ntokozo Ndlovu

British journal of clinical pharmacology（2023）

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摘要

This is the first study on the prevalence of DIC and associated genetic biomarker predictive evaluation in Zimbabwean breast cancer patients. The genetic frequencies observed in our study were different to that reported in other populations. A larger sample size with a longer follow up time will be necessary in future studies.

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关键词

Anthracyclines,Zimbabwe, Africa, polymorphisms,cardiology,cardiovascular health,genetics,risk monitoring

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