Assessment of Combined Karyotype Analysis and Chromosome Microarray Analysis in Prenatal Diagnosis: A Cohort Study of 3710 Pregnancies.

Jin Wang,Danni Wang, Yan Yin,Yi Deng,Mengling Ye,Ping Wei,Zhuo Zhang,Chun Chen,Shengfang Qin,Xueyan Wang

Genetics research（2022）

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摘要

Conventional G-banding karyotyping and CMA have their own advantages and limitations. A combination of karyotype analysis and CMA can increase the detection rate of chromosome abnormalities and make up for the limitation of signal detection.

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关键词

chromosome microarray analysis,combined karyotype analysis,prenatal diagnosis,cohort study

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