Cerebral Palsy and bisphosphonates - and what can be learned from other types of secondary osteoporosis in children: a scoping review.

Jakob B. Granild‐Jensen,Line K. Pedersen,Bente Langdahl,Jakob Starup‐Linde,Gija Rackauskaite,Stense Farholt,Charlotte Søndergaard,Esben T. Vestergaard,Bjarne Møller‐Madsen

Acta paediatrica (Oslo, Norway : 1992)（2023）

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摘要

Meta-analysis consistently showed significant BMD increases with bisphosphonates in children with secondary osteoporosis. Direct evidence of the effect of bisphosphonates on reducing fractures is lacking. We found no reports of long-term adverse events yet longer studies are needed.

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关键词

Bisphosphonate,Cerebral Palsy,bone mineral density,children,secondary osteoporosis

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