Association between DIO2 Thr92Ala polymorphism and hypertension in patients with hypothyroidism: Korean Genome and Epidemiology Study.

Young Mi Kang,Bon Seok Koo,Hyon-Seung Yi,Jung Tae Kim,Boyoung Park,Ju Hee Lee,Minho Shong,Yea Eun Kang

The Korean journal of internal medicine（2023）

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摘要

Commonly inherited variation in the DIO2 gene is associated with high blood pressure and prevalence of hypertension in patients with hypothyroidism. Our results suggest that genetic variation in the hypothalamic-pituitary-thyroid pathway in influencing susceptibility to hypertension.

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关键词

Blood pressure,Hypertension,Hypothyroidism,Iodothyronine deiodinase type II

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