Labile plasma iron and echocardiographic parameters are associated with cardiac events in β-thalassemic patients.

Francesca Ferrara,Francesca Coppi, Roberta Riva,Paolo Ventura,Andrea Ricci,Anna Vittoria Mattioli,Marisa Talarico, Cinzia Garuti,Mirco Bevini,Vincenzo Rochira,Elena Buzzetti,Antonello Pietrangelo,Elena Corradini

European journal of clinical investigation（2023）

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摘要

LPI, Hb levels and echocardiographic parameters assessing cardiac remodelling are associated with cardiac events in adult TM and TI patients. LPI might represent both a prognostic marker and a potential target for novel treatment strategies. Further studies are warranted to confirm our findings on larger populations.

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关键词

anaemia,cardiac complications,iron,labile plasma iron,myocardial hypertrophy,non-transferrin-bound iron,thalassemia

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