A new method for preparing a rat intracerebral hemorrhage model by combining focused ultrasound and microbubbles.

Yao He,Jie Yang, Fengying Hu,Min Liao, Yuru Nie,Xiaoxia Zhu,Tao Zhang, Keer Song,Qinxi Li,Xiaojie Li,Chenghan Mei,Zhe Wu,Qiang Lu,Zhihui Zhong

Animal models and experimental medicine（2023）

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摘要

A rat ICH model was successfully prepared using the μBs assisted FUS treatment, and edaravone had a therapeutic effect on this model. This model can be used to study the pathophysiological mechanism of ICH-related diseases and in preclinical research on related new drugs.

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关键词

ICH model,focused ultrasound (FUS),microbubbles (μBs),rat

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