Does metabolite matter? Defining target itraconazole and hydroxy-itraconazole serum concentrations for blastomycosis.
Mycoses（2023）
摘要
This study supports an itraconazole therapeutic target combining itraconazole and hydroxy-itraconazole >1.0 mcg/ml for blastomycosis treatment.
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关键词
Sporanox,blastomycosis,hydroxyitraconazole,itraconazole,tandem mass spectrometry,therapeutic drug monitoring
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