CD98 defines a metabolically flexible, proinflammatory subset of low-density neutrophils in systemic lupus erythematosus.

Katherine R Martin,Jessica A Day,Jacinta A Hansen,Damian B D'Silva, Huon L Wong,Alexandra Garnham,Jarrod J Sandow,Brunda Nijagal,Nicholas Wilson,Ian P Wicks

Clinical and translational medicine（2023）

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摘要

CD98 provides a phenotypic marker for LDN that facilitates identification of this population without density-gradient separation and represents a novel therapeutic target to limit its pathogenic capacity.

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关键词

CD98,granulocyte colony-stimulating factor,low-density neutrophils,systemic lupus erythematosus

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