Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation.

Clinical chemistry and laboratory medicine（2023）

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摘要

We conclude that serum proteins identified using multiplex proteomics, particularly SLAMF7, IL-1ra, BTN3A2 and DAB2, may potentially predict aGVHD.

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关键词

Proteomics,acute graft-vs.-host disease,allogeneic hematopoietic cell transplantation (HCT),biomarkers,proximity extension assay

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