Wheat ergot fungus-derived and modified drug for inhibition of intracranial aneurysm rupture due to dysfunction of TLR-4 receptor in Alzheimer's disease.

Sandip Debnath,Devesh Sharma,Somdatta Yashwant Chaudhari,Ritika Sharma, Amir Afzal Shaikh,Rahul Subhash Buchade,Kavindra Kumar Kesari,Abdel-Fattah M Abdel-Fattah,Mohammad Algahtani,Mayyadah Mheidat,Rawidh Alsaidalani,Tapas Paul,Amany A Sayed,Mohamed M Abdel-Daim

PloS one（2023）

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摘要

As a result of this, the results of our research may be relevant for future research into the efficacy of 2-bromoergocryptine mesylate as a potential lead treatment for TLR4 receptors in intracranial aneurysm rupture in AD.

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