T Cells Immunophenotyping and CD38 Overexpression as Hallmarks of the Severity of COVID-19 and Predictors of Patients' Outcomes.
Journal of clinical medicine(2023)
摘要
Decreased T cell count, specifically CD8 T cell (Tc), with T cell overactivation which was indicated by CD38 overexpression on CD4 and CD8 T cells had a substantial prognostic role in predicting severity and mortality among COVID-19 patients. These findings can provide a preliminary tool for clinicians to identify high-risk patients requiring vigilant monitoring, customized supportive therapy, or ICU admission. Studies on larger patient groups are needed.
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关键词
CD38,COVID-19,T cells,T-cytotoxic (CD8+),T-helper (CD4+)
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