Striking membrane defects in AdipoR-deficient cells.

Mario Ruiz,Dimitra Panagaki,Johanna L Höög,Marc Pilon

Journal of lipid research（2023）

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摘要

Membrane homeostasis defects likely underly numerous conditions. AdipoR1 and AdipoR2 sense excesses of saturated fatty acids in phospholipids and correct such imbalance by generating sphingosine 1-phospate (S1P) that promotes fatty acid desaturation via SREBP and PPARγ (1-3).

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关键词

striking membrane defects,cells,adipor-deficient

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