Comparison of first-line treatments for elderly patients with diffuse large B-cell lymphoma: A systematic review and network meta-analysis.

Yangyang Wang,Xiyang Ren,Keke Huang,Xue Liang,Lianfang Pu,Linhui Hu,Zhimin Zhai

Frontiers in immunology（2022）

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摘要

The findings of our meta-analysis indicated that R2CHOP21 provided the best disease control in PFS and represented an optimal first-line treatment option in the elderly with DLBCL. Furthermore, RCOMP, RminiCEOP and RCHOP21 exhibited lower rates in different 3-4 grade AEs and might be reasonable treatment options in the elderly with poor general conditions.

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关键词

clinical decision-making,diffuse large B-cell lymphoma,monoclonal antibody,network meta-analysis,therapy

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