Effect of urolithin A on the improvement of vascular endothelial function depends on the gut microbiota.

Yuichiro Nishimoto,Kota Fujisawa,Yuichi Ukawa,Masatake Kudoh,Kazuki Funahashi,Yoshimi Kishimoto,Shinji Fukuda

Frontiers in nutrition（2022）

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摘要

Urolithin A intake alters the gut microbiota and improves their alpha diversity. In addition, the effect of UA on VEF correlated with the individual gut microbiota. Our results have practical implications for a new approach to providing healthcare that focuses on intestinal environment-based diet therapy.

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关键词

flow-mediated vasodilatation,gut microbiota,organic acids,urolithin A,vascular endothelial function

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