Neurofilament light level correlates with brain atrophy, and cognitive and motor performance.

Frontiers in aging neuroscience(2022)

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摘要
NfL was strongly related to global gray matter and hippocampal atrophy, but not to WMH severity. NfL was also associated with motor performance. Our results suggest that NfL is independently associated with brain atrophy and functional mobility, but is not a reliable marker for cerebral small vessel disease.
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关键词
brain atrophy,cognitive performance,motor performance,neurofilament light,small vessel disease,white matter hyperintensities
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