Platelet function studies in myeloproliferative neoplasms patients with Calreticulin or JAK2V617F mutation

Research and Practice in Thrombosis and Haemostasis(2023)

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摘要
•Patients with MPN with CALR mutations are at lower risk of thrombosis than patients with JAK2V617F.•Platelet function analyses were conducted in 16 patients with CALR MPN.•Analysis revealed platelet function defects in patients with MPN compared with that in controls.•We observed minor differences in platelets between patients with CALR and patients with JAK2V617F.
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关键词
blood platelets,calreticulin,JAK2V617F mutation,myeloproliferative neoplasms,platelet aggregation,thrombosis
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