Cell and cell-derivative-based therapy for liver diseases: current approaches and future promises.

Ensieh Zahmatkesh,Niloofar Khoshdel Rad,Nikoo Hossein-Khannazer,Mehdi Mohamadnejad,Roberto Gramignoli,Mustapha Najimi,Reza Malekzadeh,Moustapha Hassan,Massoud Vosough

Expert review of gastroenterology & hepatology（2023）

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摘要

Promising application of stem cell-based techniques including iPSC technology has been integrated into novel techniques such as gene editing, directed differentiation, and organoid technology. iPSCs offer promising prospects to represent novel therapeutic strategies and modeling liver diseases.

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关键词

Primary hepatocyte,extracellular vesicles,liver cell therapy,liver organoids,mesenchymal stromal cells,pluripotent stem cells

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