Peptomer substrates for quantitative pattern-recognition sensing of proteases.
Chemical communications (Cambridge, England)(2023)
摘要
The utility of active proteases as biomarkers is often limited by overlapping substrate specificity. Here, this feature is leveraged to develop a quantitative pattern-recognition sensing system driven by the degradation patterns of peptide-peptoid hybrid substrates to classify proteases and estimate their concentration by multivariate data analysis.
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关键词
proteases,pattern-recognition
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