Plasma neurofilament light significantly decreases following treatment in Lyme neuroborreliosis and is not associated with persistent symptoms.

Helene Mens,Lasse Fjordside,Rosa Gynthersen,Mathilde Ørbaek,Åse Bengaard Andersen,Ulf Andreasson,Kaj Blennow,Finn Sellebjerg,Henrik Zetterberg,Anne-Mette Lebech

European journal of neurology（2023）

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摘要

Plasma neurofilament light chain decreases following antibiotic treatment in LNB and is not associated with reporting persistent symptoms. It was therefore speculated that it may prove useful as a treatment response biomarker in LNB.

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关键词

Lyme neuroborreliosis,biomarker,neurofilament light chain,neuroinflammation,persistent symptoms

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