Up-regulation of FGF7 induced Intra-vesical Prostatic Protrusion of Benign Prostatic Hyperplasia via the ERK1/2 signaling pathway.

Zheng Zhou, Lei Wu,Sheng Zhao,Shu-Jie Xia,Lei Pan, Min Chen,Yi-Ping Zhu,Jun-Tao Jiang,Fei Shi

Gerontology（2023）

引用 0|浏览12

暂无评分

摘要

Our data revealed a novel amplification effect, namely stromal cells derived FGF7 promotes epithelial cell proliferation as well as stromal cell phenotype which eventually induced IPP formation. And targeting FGF7 significantly reduced epithelial to stromal transition, also providing a potential therapeutic target for BPH progression.

查看译文

关键词

Benign prostatic hyperplasia,Intravesical prostatic protrusion,RNA sequencing,Epithelial-mesenchymal transition,ERK signaling

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要