Preclinical evaluation of a third-generation absorbable antibacterial envelope.

Charles J Love,Ibrahim Hanna,George Thomas,Arnold J Greenspon,Melissa Christie,Jonathan Goodman,Matthew Christopherson,Vasanthi Balaji,Shira Skulsky,Matthew Sanders,Carrie Bauer, William Schindeldecker,Nicole Kirchhof,M Rizwan Sohail

Heart rhythm（2023）

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摘要

The third-generation TYRX absorbable antibacterial envelope demonstrated equivalent preclinical performance to the second-generation envelope. Antibiotic elution curves were similar, elution was above MIC for 7 days, infections were reduced compared to no envelope, and acceptance criteria for migration, rotation, and absorption were met.

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关键词

Cardiac implantable electronic device,Infection,Preclinical evaluations,Stabilization,TYRX

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