Akkermansia deficiency and mucin depletion are implicated in intestinal barrier dysfunction as earlier event in the development of inflammation in interleukin-10-deficient mice.
Frontiers in microbiology（2022）
摘要
Gut microbiota alterations and mucin depletion are associated with early intestinal barrier dysfunction and precede overt gut inflammation in this animal model of IBD.
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关键词
Akkermansia muciniphila,gut microbiome,inflammatory bowel disease,interleukin-10-deficient mice,intestinal barrier,mucin
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