Placebo-Controlled Effectiveness of Idiopathic Normal Pressure Hydrocephalus Shunting: A Randomized Pilot Trial.

Mark Luciano,Richard Holubkov,Michael A Williams,Jan Malm,Sean Nagel,Abhay Moghekar,Anders Eklund, Thomas Zwimpfer,Heather Katzen,Daniel F Hanley,Mark G Hamilton

Neurosurgery（2023）

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摘要

This multicenter, randomized pilot study demonstrates the effectiveness, safety, and feasibility of a placebo-controlled trial in iNPH, and found a trend suggesting gait velocity improves more in the open shunt group than in the placebo group.

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关键词

NPH (normal pressure hydrocephalus),Hydrocephalus,Shunting,RCT,Placebo,VPS (ventriculoperitoneal shunting)

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