Shifting gears: Study of immune system parameters of male habitual marathon runners.

Ioannis Panagoulias,Nikolaos Charokopos,Iason Thomas,Panagiota I Spantidea,Anne-Lise de Lastic,Maria Rodi,Spyridoula Anastasopoulou,Ioanna Aggeletopoulou, Charalampos Lazaris,Kiriakos Karkoulias,Lydia Leonidou,Neoklis A Georgopoulos,Kostas B Markou,Athanasia Mouzaki

Frontiers in immunology（2022）

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摘要

Compared with controls, marathoners live with permanent changes in certain immune parameters. Marathoners exhibit a stable pro-inflammatory cytokine polarization that increases after the race and is counterbalanced by increased numbers of Tregs overexpressing FoxP3 and having increased suppressive capacity.

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关键词

T cells,Tregs,cytokines,lymphocytes,strenuous exercise,transcription factors ROR-γt/Tbet/GATA-3/FoxP3/Ets-2

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