Pegfilgrastim on febrile neutropenia in pediatric and adolescent cancer patients: a systematic review and meta-analysis.

Xia Zhu,Weiling Zhang,Yi Zhang,Yizhuo Wang,Huimin Hu,Jing Li,Yan Zhou,Tao Han,Dongsheng Huang

Hematology (Amsterdam, Netherlands)（2023）

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摘要

There was no difference between pegfilgrastim and filgrastim for the rate of FN. The use of pegfilgrastim was still associated with rates of FN, grade 4 FN, severe neutropenia, and treatment delays due to FN in pediatric cancer patients.

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关键词

Granulocyte colony-stimulating factor,adolescents,cancer treatment,children,febrile neutropenia,meta-analysis,neutropenia,treatment delay

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