Infants with Congenital Adrenal Hyperplasia Exhibit Thalamic Discrepancies in Early Brain Structure.

Vidya Rajagopalan,Lloyd N Overholtzer,William S Kim,Jessica L Wisnowski,Trevor A Pickering,Nicole R Fraga,Joyce Javier,Liza Mackintosh,Christine Mirzaian,Mitchell E Geffner,Mimi S Kim

Hormone research in paediatrics（2023）

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摘要

Infants with CAH exhibit smaller thalamic regions from early life, suggesting a prenatal influence on brain development in CAH. Thalamic emergence at 8-14 weeks makes the region particularly vulnerable to changes in the intrauterine environment, with potential implications for later maturing brain regions. These changes may take time to manifest, meriting longitudinal study through adolescence in CAH.

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infants,adrenal

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