Hyperactivation of YAP/TAZ Drives Alterations in Mesangial Cells through Stabilization of N-Myc in Diabetic Nephropathy.

Seunghyeok Choi,Seon Pyo Hong,Jung Hyun Bae,Sang Heon Suh,Hosung Bae,Kyung Pyo Kang,Hyuek Jong Lee,Gou Young Koh

Journal of the American Society of Nephrology : JASN（2023）

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摘要

Our findings shed light on how high blood glucose in diabetes mellitus leads to DN and support a rationale that lowering blood glucose in diabetes mellitus could delay DN pathogenesis.

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关键词

diabetic nephropathy, diabetic glomerulopathy, mesangial cells

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