Untargeted, High-Resolution Metabolomics in Pediatric Eosinophilic Esophagitis.

Elizabeth M Sinclair,Catherine C Cohen,ViLinh Tran,Dean P Jones,Jessica A Alvarez,Rishikesan Kamaleswaran,Milad Ghiasi Rad,Patrice G Kruszewski,Miriam B Vos

Journal of pediatric gastroenterology and nutrition（2023）

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摘要

In this pilot study, we found differences in metabolites involved in glycerophospholipid and inflammation pathways in pediatric patients with EoE using untargeted metabolomics, as well as overlap with amino acid metabolome alterations found in atopic disease.

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关键词

allergy,eosinophilic esophagitis,esophagus,metabolomics,pediatrics

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