Closed hyperthermic intraperitoneal chemotherapy with CO2 recirculation system compared with the open Coliseum technique in peritoneal malignity treatment

•Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is the treatment of choice in peritoneal carcinomatosis.•The Closed HIPEC technique was introduced due to the need to improve the safety of the staff in the operating room.•The PRS Closed HIPEC creates a turbulent flow with CO2 recirculation that allows an optimal diffusion and penetration of the cytotoxic drug.•The PRS Closed HIPEC technique with CO2 recirculation could achieve better local control in the treatment of peritoneal malignancies compare with Open HIPEC techniques.