Anti-inflammatory actions of Pentosan polysulfate sodium in a mouse model of influenza virus A/PR8/34-induced pulmonary inflammation.

Ravi Krishnan,Catherine J M Stapledon,Helen Mostafavi,Joseph R Freitas,Xiang Liu,Suresh Mahalingam,Ali Zaid

Frontiers in immunology（2023）

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摘要

The systemic and local anti-inflammatory actions of PPS may regulate acute and post-acute pulmonary inflammation and tissue remodeling mediated by PR8 infection, which warrants further investigation.

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关键词

Pentosan polysulfate sodium,acute inflammation,chronic lung inflammation,cytokines and chemokines,immune cell infiltrate,influenza A virus,lung consolidation,lung fibrosis

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