STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma.

Weiman He, Yijia Sun, Jiawei Ge,Xuejie Wang,Bo Lin,Shuang Yu,Yanbing Li,Shubin Hong,Haipeng Xiao

Frontiers in endocrinology（2023）

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摘要

Our study demonstrates STRA6 may serve as a prognostic marker for BRAF-mutated PTC, which may drive thyroid carcinogenesis activation of oncogenic pathway and regulation of tumor immunosuppressive microenvironment.

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关键词

BRAF mutation,STRA6,papillary thyroid carcinoma (PTC),prognosis,tumor immune microenvironment

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