Rapid disease progression on immune checkpoint inhibitors in young patients with stage IV melanoma.

Devayani Machiraju,Sarah Schäfer,Philip Beckhove,Jasmin Roth,Carsten Schulz,Jessica C Hassel

Frontiers in medicine（2023）

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摘要

Young patients with stage IV melanoma may experience shorter progression-free survival upon ICI treatment compared to patients above 40 years and are characterized by fewer basophils and memory T cells in the blood.

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关键词

age,immune checkpoint inhibitors (ICI),melanoma,memory T cells,soluble immune checkpoint proteins,young adults

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