Development of desquamation with Staphylococcus aureus colonization in patients with atopic dermatitis under treatment with upadacitinib.

We report two patients with atopic dermatitis who were treated with upadacitinib, and later developed desquamation of the face with Staphylococcus aureus colonization. Treatment with ciclosporin and antibiotics was unsuccessful, but both patients improved when treatment was switched to dupilumab.