Stoking inflammasome fires in the COVID-19 neighborhood.
Cell host & microbe（2023）
摘要
The cellular and molecular sources of elevated IL-1β and IL-6 in COVID-19 remain unclear. In this issue of Cell Host and Microbe, Barnett et al. determine how immune cells sense SARS-CoV-2 infection in neighboring epithelial cells to trigger inflammasome signaling and IL-1β release, which in turn promotes IL-6 release.
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