Dectin-1 Acts as a Non-Classical Receptor of Ang II to Induce Cardiac Remodeling.

Shiju Ye,He Huang,Xue Han,Wu Luo,Lili Wu,Yang Ye,Yingchao Gong,Xia Zhao,Weijian Huang,Yi Wang,Xiaohong Long,Guosheng Fu,Guang Liang

Circulation research（2023）

引用 5|浏览15

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摘要

Our study has discovered dectin-1 as a new nonclassical receptor of Ang II and a key player in cardiac remolding and dysfunction. These studies suggest that dectin-1 may be a new target for treating hypertension-related heart failure.

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angiotensin II,dectin-1,heart failure,inflammation,macrophages,mutagenesis

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