Comparison of Two Modes: “Pressure-Regulated Volume-Controlled” and “Adaptive Support Ventilation” in Intensive Care Units’ Patients

Background: Nowadays, the use of mechanical ventilation devices has a vital use in the treatment of patients hospitalized in intensive care units, while different modes of mechanical ventilation devices had different outcomes, thus this study aimed at comparing two modes of mechanical ventilation, that is the outcome of pressure regulated volume-controlled (PRVC) and Adaptive support ventilation (ASV) on hemodynamic changes and time taken to separate the patient from the device in the intensive care unit. Methods: This study is a single-blind randomized clinical trial conducted in Alzahra hospital during 2018-2019. The research population of the study included 74 patients admitted to the intensive care unit who were selected by convenience sample. The patients were ramdomly divided into two groups. The device parameters were adjusted on PRVC mode for the first group and ASV mode for the second group. The data were compared between two groups using. Data were analyzed using Chi-square tests, T-test, and repeated measures of ANOVA and ANCOVA. Findings: There was no significant difference between the two groups at different intervals in terms of systolic and diastolic blood pressure and heart rate, pH and HCO3, RAMSY score. The analysis of variance with repeated observations showed that both, the group and time had significant effects on SPO2 and PCO2. The average length of time connected to the mechanical ventilation device and the duration of hospitalization in the ASV group was significantly lower than the PRVC Group. Conclusion: The ASV mode more than PRVC mode decreased the length of stay and need for ventilation of hospitalized patients in intensive care units.