Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type.

Kristin Kaasen Jørgensen,Marte Lie Høivik,Adity Chopra,Jūratė Šaltytė Benth,Petr Ricanek,Prof Bjørn Moum,Ingrid Jyssum,Nils Bolstad,David John Warren,Prof John T Vaage,Prof Ludvig A Munthe,Prof Knut E A Lundin,Karoline Anisdahl,Silje Watterdal Syversen,Guro Løvik Goll,Fridtjof Lund-Johansen,Asle W Medhus,Prof Jørgen Jahnsen

Scandinavian journal of gastroenterology（2023）

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摘要

Patients with CD had an attenuated humoral response to SARS-COV-2 vaccination as compared to patients with UC. The lack of association between serum levels of biologics and serologic response indicates vaccination regardless of proximity to drug administration.

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关键词

Immunogenicity,Inflammatory bowel disease,SARS-CoV-2 vaccine,biologic medication

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