Vascular Smooth Muscle TRPV4 (Transient Receptor Potential Vanilloid Family Member 4) Channels Regulate Vasoconstriction and Blood Pressure in Obesity.

Yifei Zhu,Yuan Chu,Sheng Wang,Junjian Tang,Hu Li,Lei Feng,Fan Yu,Xin Ma

Hypertension (Dallas, Tex. : 1979)（2023）

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摘要

Our data identify TRPV4 as a regulator of vascular contraction in both physiological states and pathologically obese mice. TRPV4 contributes to the ontogeny of vasoconstriction and hypertension induced by TRPV4 over-expression in obese mice mesenteric artery.

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关键词

blood pressure,hypertension,myography,obesity,vasoconstriction

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